Billionaire Bryan Johnson undergoes complete plasma replacement to combat aging: Here’s how ‘total plasma exchange’ works

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Billionaire Bryan Johnson undergoes complete plasma replacement to combat aging: Here’s how ‘total plasma exchange’ works.

Billionaire Bryan Johnson’s Bold Experiment: “Super Clean” Plasma and Age Reversal

Bryan Johnson, a tech entrepreneur and longevity enthusiast, has once again made headlines with a new twist in his quest to slow down biological ageing. In a recent social media post, Johnson revealed details about his latest total plasma exchange (TPE), a medical procedure he believes is essential to his ambitious anti-ageing regimen.

Plasma Purity: “Liquid Gold” That Surprised Experts

Johnson, sharing his excitement on the social media platform X, called his plasma “liquid gold” and recounted a remarkable interaction at the clinic. After undergoing a TPE session, where his plasma was removed and analyzed, the lab technician marveled at the quality of the sample.

According to Johnson, the technician, who had performed TPE for nearly a decade, found the billionaire’s plasma so clean that he hesitated to dispose of it. “He said my plasma was the cleanest he had ever seen—by far—and kept imagining the positive impact it could have,” Johnson wrote. To illustrate his point, Johnson posted a photo holding a bag of pale, straw-colored plasma, claiming it possessed regenerative properties.

Project Blueprint: A $2 Million Quest for Longevity

The plasma exchange is just one component of Johnson’s meticulously designed anti-ageing plan, Project Blueprint. Known for his obsession with longevity, Johnson reportedly invests more than $2 million annually in this program, which consists of a highly controlled diet, rigorous exercise routines, and cutting-edge experimental therapies. His ultimate goal is to reverse his epigenetic age—an indicator of biological ageing—and slow the decline of his body’s functions.

As part of this program, Johnson undergoes regular plasma exchange sessions, believing that they help remove toxins and rejuvenate his body. In the most recent session, his plasma was replaced with albumin, a substitute fluid often used in medical procedures.

“TPE removes all my plasma and replaces it with albumin. The objective is to flush out toxins from the body,” Johnson explained, acknowledging that while the science is still developing, he believes these treatments are crucial to slowing the ageing process.

A Family Experiment: Multigenerational Plasma Exchange

Johnson’s fascination with plasma doesn’t end with his treatments—he has also involved his family in his experiments. Earlier this year, he performed what he described as the world’s first multigenerational plasma exchange by using plasma from his 17-year-old son. In a controversial move, Johnson referred to his son as his “blood boy,” a term implying that the younger plasma could enhance Johnson’s anti-ageing progress.

Not stopping there, Johnson injected one liter of his plasma into his father, claiming that the procedure reduced his father’s biological age by 25 years. Johnson believes these results demonstrate the transformative power of plasma in reversing age-related decline.

What is Total Plasma Exchange (TPE)?

TPE is a medical procedure typically used to treat autoimmune disorders and certain blood conditions, but it has recently gained attention in the field of regenerative medicine and anti-ageing. During TPE, the patient’s plasma is removed and replaced with either donor plasma or a substitute fluid like albumin. The goal is to eliminate toxins, immune complexes, or other unwanted substances from the body.

While the long-term impact of TPE on ageing remains uncertain, some experts speculate that removing old plasma could slow cellular ageing and promote regeneration. Johnson believes the procedure is pivotal in his quest to rewind biological ageing and extend the human lifespan.

Debate and Controversy: Science vs. Speculation

Johnson’s experiments have sparked intense debate within the medical and scientific communities. While some researchers are optimistic about the potential of plasma-based therapies for longevity, others warn that the science is still emerging, and that conclusive evidence is lacking.

In a recent controversy, Reliance on younger plasma—as in the case of Johnson’s use of his son’s blood—has drawn criticism, with some questioning the ethics and risks involved. Additionally, experts caution that regular plasma exchanges may carry health risks, including infections or immune responses, and more research is needed to understand their full implications.

Looking Ahead: The Future of Regenerative Medicine

Bryan Johnson’s public experiments, though controversial, have shone a spotlight on regenerative medicine and its potential to redefine ageing. His bold initiatives have raised critical questions about the future of longevity science: Can ageing truly be reversed, and at what cost? Will plasma exchanges become a mainstream anti-ageing treatment, or will they remain a speculative approach used by a select few?

Bryan Johnson

Regardless of the outcome, Johnson’s efforts have ignited public curiosity about the possibilities of extending the human lifespan, pushing the boundaries of what modern medicine can achieve. Whether these procedures will yield long-term benefits or merely serve as intriguing experiments remains to be seen. For now, Johnson is determined to lead the way in what he sees as a new frontier of human rejuvenation.

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